11^th World Congress on Breast Cancer October 04-05, 2021 Barcelona, Spain

Biography:

Jawad Fardin is a Senior at Department of Adult medicine, French Medical Institute for Mothers and Children, Kabul, Afghanistan. As a Clinician, he has rich experience of treating oncology patient and one of the first oncology doctors in Afghanistan. He worked in first and only oncology center in Jamhoriat Hospital, He was aslo joened as medical director in Agha Medical Center and currently working in French Medical Institute for Mothers and Children. He independently completed a research project entitled “Factors contributing to delayed diagnosis and treatment of breast cancer and its outcome in Jamhoriat hospital Kabul, Afghanistan”.

Abstract:

Over 60% of patients with breast cancer in Afghanistan present late with advance stage III and IV, a major cause for the poor survival rate. The objectives of this study were to identify the contributing factors for the diagnosis and treatment delay and its outcome. This cross sectional study was conducted on 318 patients with histologically confirmed breast cancer in oncology department of Jamhoriat hospital, which is the first and only national cancer center in Afghanistan, data were collected from medical records and interview conducted with women diagnosed breast cancer , linear regression and logistic regression were used for analysis. Patient delay was defined as time from first recognition of symptoms until first medical consultation and doctor form first consultation with a health care provider until histological confirmation of breast cancer .The mean age of patients was 49.2+_ 11.5years. the average time for final diagnosis of breast cancer was 8.5 months, most patients had ductal carcinoma 260.7 (82%). factors associated with delay were low education level 76% poor socioeconomic and cultural conditions 81% lack of cancer center 73% lack of screening 19%. the stage distribution was as follow stage IV 4 22% stage III 44.4% stage II 29.3% stage I 4.3%. Complex associated factors were identified to delayed diagnosis of breast cancer and increased adverse outcome consequently. raising awareness and education in women, establishment of cancer centers and providing accessible diagnosis service and screening, training of general practitioners ; required to promote early detection , diagnosis and treatment.

Biography:

Maha Abdel Hadi from Department of Surgery in Imam Abdul Rahman Bin Faisal Universityand he lives in Kingdom of Saudi Arabia.

Abstract:

The fast pace of urbanization in many developing countries coupled with the imposed changes in life style has resulted in many alterations in disease patterns. Breast cancer is one of the diseases that has shown increasing incidence over the last decades with young age and advanced disease at initial presentations. The scarcity of specialized treatment Centers in the Region further impacts negatively on the outcomes limiting the surgical options to liberal adoption of mastectomies. According to the International Atomic Energy Agency (IAEA) Consensus, the number of Radiation Oncology centers worldwide is scarce and mainly clustered in developed countries. Developing countries are deprived from adequate centers to cover the population needs to radiation treatments. Based on the emerging many studies and strictly adhering selection criteria intraoperative radiotherapy (IORT) has proven efficient, convenient, cost effective and can be used in conventional operating rooms. It spares or shortens the patients the long sessions of external beam radiation while providing equally effective outcomes. In developing countries, the lack of structured Breast cancer awareness programs coupled by the liberal adoption of mastectomies for young females results in patients shying away until the disease advances. IORT is an appealing treatment method which will propagate breast conserving therapy (BCT), early detection and restricting unnecessary mastectomies. Promoting such modality helps to overcome the shortcomings encountered due to the limited radiation oncology centers in the area. Alternatively, due to the young age at presentation IORT may be of more benefit when used as boost therapy, this will reciprocally reduce the burden inflicted on radiation oncology centers by the expanding patient population.

Biography:

Mahish Karim works as  Oncology Resident in Surrey at United Kingdom.

Abstract:

Background:

Locally advanced breast cancer patients with Stage 3 ,high disease burden are required to have  Mri head staging scans prior to starting the treatment. One of the biggest obstacle is the time it takes to get the mri scans.

Audit was performed to review the previous mri head scan reports  and see if waiting time could be reduced by omitting mri head scans prior to the treatment.

Methods:

73 breast cancer patients,both neoadjuvant and adjuvant were reviewed   from period of Dec 2019 -Dec 2020 at Royal Surrey County Hospital ,Guildford. Mri head reports performed on 14 high risk patients were reviewed.

Results:

Out of 73 locally advanced breast cancer patients ,14 had mri head scans prior to commencemnet of treatment. All 14 mri head reports were negative for metastasis.

Conclusion:

All mri reports were negative for metastasis . Despite high risk for CNS mets in a certain cohort of patients , no evidence was found to suggest that treatment delay is justified.

Biography:

Professor of Psychiatric & Mental Health Nursing, The  ex- Dean Faculty of Nursing, Suez Canal University, Ismailia. Egypt. Now the Vice Dean, Post- graduate and Research Affairs, also the Visiting Scientist, Queen’s University School of Nursing, Kingston, ON Canada. A consultant in Nursing Education for Maastricht University.  Active Membership of  Psycho‐Oncology Society . Reviewer of many international & national Journals  for example in Archives of Psychiatric Nursing Journal the editor the faculty of nursing scientific journal    . My research interest in oncology area,  community & Psychiatry mental health Nursing , human sexuality & Psych- Oncology Nursing.  

Abstract:

Background: Breast cancer disease and its treatment often turns into a psychological health problems that affect both acceptance of body image and satisfaction of sexual life. The Psychiatric consultation liaison nurse play an important role in enhancement the psychological problems derived from breast cancer and provide effective management of care.

Aim of the study: Determine effect of breast cancer lines of  treatment on body image and sexual life among married women

Setting: The study was conducted in Oncology Unit and Oncologic Outpatient Clinics at Suez Canal University Hospitals, Ismailia, Egypt.

Sample: Accidental sample of 125 mastectomies women were selected in this study.

Tools: Data was collected using one to one interview method to fill four structured questionnaires and rating scale. Tools of data collection were Personal, Sexual and Clinical Data- Breast Impact of Treatment Scale (BITS), Female Sexual Function Index (FSFI) and Women's and Partners Reactions Post Mastectomy (developed by the researcher).

Results: More than half of studied women have low satisfaction about their level of body image, about one third  of them were unsatisfied with their sexual life. Most of the studied women expressed unsatisfaction about desire, orgasm and lubrication. There is statistical significance relation between, body image satisfaction and treatment received , women and husbands' reactions, Female Sexual Function Index.

Conclusion: Cancer Breast Women with mastectomy received other chemical and radiological lines of treatment suffer many problems which affect their satisfaction with their body image and physical fittness.

Recommendation: Psychiatric Liaison Nursing Service should be generalized to all hospitals especially in critical care units. 

Biography:

Mervat Al Saleh is from Kuwait University and she is the most expertise member in Breast Cancer from Kuwait.

Abstract:

Breast cancer surgery must now be carried out with due consideration of cosmetic outcome without oncological compromise. Disfiguring and mutilating excisions are no longer justified and are unacceptable. Surgeons must balance the oncological and cosmetic needs of individual patients and understand the principles thereof. It is essential that the surgeon discusses management options with the concerned individual and arrive at a balanced judgment which considers the age, medical and psychological background in coherence with the desires and expectations of the woman involved. Breast augmentation could be done by either silicon or saline implants. The cheapest and non-surgical procedure for augmentation is breast injection, autologous fat transplantation (micro-lipo-injection) with stem cell breast augmentation. Autologous breast augmentation procedure uses a woman’s own fat instead of breast implants to enlarge the size of the breasts. The disadvantages of breast injection are the following: patients are more prone to get infected, less satisfied and poorly screened. Unfortunately, unprofessional workers use this technique with unapproved materials to enlarge breast size.  These substances are hormones or unknown materials in nature like minerals oil, Vaseline and liquid silicon. 32 patients were included in this 2-year study with pain, infected area, inflammations, and other symptoms. All patients underwent investigations, ultrasound, mammogram, and MRI. The treatment of late and delayed adverse effects is challenging. Breast enlargement injections may seem like a simple and economic solution for increasing bust size when compared to invasive surgery, but they are by no means safe. It is highly advisable to look for other breast enlargement techniques before considering breast enlargement injections due to the dangerous side effects caused by the latter.

Biography:

Afrah Aladwani is from University of Strathclyde, UK.

Abstract:

Introduction: Breast cancer is a heterogeneous disease that exhibits different biological characteristics, and hence different responses to therapeutic agents. Understanding histological and molecular characteristics has led to introducing more classifications and subtypes of breast tumours in the treatment guidelines and changing aspects of treating patients from applying standardized treatment protocols to tailoring individualized treatment protocols. Questions were raised regarding the impact of advanced age on biological changes of tumour cells. The current study compares the intrinsic subtypes of breast tumours between younger and older patients in the Kuwait Cancer Control Centre (KCCC).

Methods: In a comparative population-based cross-sectional study, a total of 180 patients with breast cancer were randomly selected and subdivided into two age categories (<60 yrs or ≥60 yrs). Principle characteristics were: newly diagnosed female patients aged 21 years and above and referred to the Medical Oncology Department in the Kuwait Cancer Control Centre (KCCC) to receive systemic treatment between April 2016 and April 2018. Individual baseline tumour characteristics, including histopathology, TNM staging, Ki67% proliferative index status, hormonal (HR) and Human Epidermal Growth Factor (HER-2) receptor status, were assessed and compared between the two age cohorts using the Chi-Square Test.

Results: On diagnosis, non-metastatic breast cancer occurred in 93.3% and 85% of older and younger patients, respectively (p-value 0.11). Invasive Ductal Carcinoma (IDC) was the most predominant histopathological subtype in both age cohorts (93.3% and 96.7% in older and younger patients, respectively). Based on the TNM staging system, a statistically significant higher rate of stage II breast cancer was detected in older patients compared to younger patients (46.5% and 28.3% respectively; p value= 0.046). The Ki67% status did not differ by age cohort, whether considering ≥14% or ≥30% over-expression. Intrinsic molecular subtypes did not differ by age with HR and HER-2 positive tumours being the most common (p-value= 0.77).

Figure 1. Comparing the proportions of HR and HER-2 receptors expression status between patients from the two age

Conclusion:

Breast cancer patients aged 60 years and above exhibited histopathological and molecular characteristics similar to younger patients in Kuwait. Also, the status of disease metastasis and proliferation did not differ by age. The only significant difference detected was the disease stage at diagnosis with more advanced non-metastatic tumours detected in younger patients.

Biography:

Slobodníková J from Faculty of the Health Care, Alexander Dubček University of Trenčín, Slovak republic.

Abstract:

Biography:

Zerko wako is from Anbessa Specialized hospital from Ethopia.

Abstract:

Background: In breast cancer patients, adherence to adjuvant hormone therapy (AHT) is uncertain. Seven of them were hormone receptor positive in every 10 patients and adjuvant hormone therapy (AHT) is prescribed for 5-10 years for a woman with breast cancer. Therefore, this research aims to examine adherence to adjuvant hormone therapy and related factors among women with breast cancer attending the Tikur Anbessa Specialized Hospital oncology center.

Method: Institutional based cross-sectional study was conducted from March -April, 2019.  Systematic random sampling technique was used to select participants. A semi-structured questionnaire was used. Medication possession ratio (MPR) was used where score ≥ 80% was adherence. Data were entered in EpiData version 4.4.2.1 and transferred to SPSS version 25, and analyzed using binary logistic regression

Result: Out of 216, 209 women with breast cancer participated in the study with response rate of 97%. The overall adherence in this study was 77.5%. Getting social support (OR=3.959, CI (1.570-9.980), being on Anastrozole (OR=0.139, CI (0.040-0.485), Getting a thorough therapeutic communication about treatment (OR=4.590, CI (1.061-19.863), undergoing mastectomy (OR=0.215, CI (0.059-0.788), having side effect (OR=0.210, CI (0.085-0.517), were found to be significantly associated with adherence to AHT.

Conclusion: In general, the overall adherence to AHT was 77.5 percent for women with breast cancer. Factors such as types of adjuvant hormone therapy, lack of side effects, mastectomy, getting social support, and thorough therapeutic communication were strongly linked with adherence to them.

Biography:

Lloyd Jenkins is a certified Naturopath and owner of the Budwig Cancer Clinic in Malaga, Southern Spain. He received authorizat ion from Dr. Johanna Budwig in August 2000 to use her protocol for treating people with all types of cancer. He has written seven books and literally hundreds of articles on how to treat cancer and all common diseases using natural therapies. He has also been on radio talk shows and has spoken at Health Care seminars and events. Lloyd is a native-born Canadian and is fluent in English,Spanish and French.

Abstract:

Biography:

Huang Wei Ling, born in Taiwan, raised and graduated in medicine in Brazil, specialist in infectious and parasitic diseases, a General Practitioner and Parenteral and Enteral Medical Nutrition Therapist. Once in charge of the Hospital Infection Control Service of the City of Franca’s General Hospital, she was responsible for the control of all prescribed antimicrobial medication and received an award for the best paper presented at the Brazilian Hospital Infection Control Congress in 1998. Since 1997, she works with the approach and treatment of all chronic diseases in a holistic way, with treatment guided through the teachings of Traditional Chinese Medicine and Hippocrates. Researcher in the University of São Paulo, in the Ophthalmology department from 2012 to 2013.Author of the theory Constitutional Homeopathy of the Five Elements Based on Traditional Chinese Medicine. Author of more than 60 publications about treatment of variety of diseases rebalancing the internal energy using Hippocrates thoughts.

Abstract:

 Introduction: Breast cancer is the most common cancer-affecting women worldwide. Western current perspectives are starting to comprehend cancer as a systemic disease from the start. In TCM, the formation of cancer is associated energy deficiencies with Heat retention. Spleen deficiency is one of the major causes of formation of Phlegm leading to the formation of tumors. There are studies associating the five elements in TCM with chakras’ energy centers and measuring the chakra, the author will be measuring the internal massive organs energy.

Purpose: To demonstrate that there are chakras’ energy deficiencies chronically present in the body of the patient with breast cancer. Also, to analyze the importance of treating the subject systemically, through the replenishment of chakras’ energy centers.

Methods: two cases report, both were female patients (42 and 56years old), with the diagnosis stress and anxiety in the first and the second with diagnosis of sub retinal fluid retention, both patients with past history of breast cancer twenty and six years ago, removed with surgery. Chakras’ energy measurement through radiesthesia procedure was done.

Results: all the chakras were in the lowest level of energy, rated in one out of eight.

Conclusion: patients with history of breast cancer have chakras’ energy centers deficient in energy and the replenishment of these chakras’ is the major importance to prevent future formation of metastasis, new cancer in other sites or the formation of any chronic diseases.

Biography:

Naomi Dempsey, MD is a hematologist/oncologist with a focus on breast cancer with the Center for Hematology and Oncology at the Lynn Cancer Institute in Boca Raton, FL. She graduated from University of Miami Miller School of Medicine as a Doctor of Medicine in 2014. She then completed her internal medicine residency at Jackson Memorial Hospital in Miami in 2018. She also has experience in breast cancer basic science research, which she conducted during medical school and residency. She graduated from hematology/oncology fellowship in June 2021. She now leads the breast cancer clinical trials initiative at the Lynn Cancer Institute.

Abstract:

Despite great success as a targeted breast cancer therapy, trastuzumab use may be complicated by heart failure and loss of left ventricular contractile function. Cardiovascular disease risk factors, advanced age, and previous anthracycline treatment predispose to trastuzumab-induced cardiotoxicity (TIC), with anthracycline exposure being the most significant risk factor. Cardiac biomarkers such as troponins and pro-BNP and imaging assessments such as echocardiogram before and during trastuzumab therapy may help in early identification of TIC. Initiation of beta-adrenergic antagonists and angiotensin converting enzyme inhibitors may prevent TIC.  Cardiotoxicity rates of other HER2-targeted treatments, such as pertuzumab, T-DM1, lapatinib, neratinib, tucatinib, trastuzumab deruxtecan, and margetuximab, appear to be significantly lower as reported in the pivotal trials which led to their approval. Risk assessment for TIC should include cardiac imaging assessment and should incorporate prior anthracycline use, the strongest risk factor for TIC. Screening and prediction of cardiotoxicity, referral to a cardio-oncology specialist, and initiation of effective prophylactic therapy may all improve prognosis in patients receiving HER2-directed therapy. Beta-blockers and ACE inhibitors appear to mitigate risk of TIC. Anthracycline-free regimens have been proven to be efficacious in early HER2-positive breast cancer and should now be considered the standard of care for early HER2-positive breast cancer. Newer HER2-directed therapies appear to have significantly lower cardiotoxicity compared to trastuzumab, but trials are needed in patients who have experienced TIC and patients with pre-existing cardiac dysfunction.

Biography:

Huang Wei Ling, born in Taiwan, raised and graduated in medicine in Brazil, specialist in infectious and parasitic diseases, a General Practitioner and Parenteral and Enteral Medical Nutrition Therapist. Once in charge of the Hospital Infection Control Service of the City of Franca’s General Hospital, she was responsible for the control of all prescribed antimicrobial medication and received an award for the best paper presented at the Brazilian Hospital Infection Control Congress in 1998. Since 1997, she works with the approach and treatment of all chronic diseases in a holistic way, with treatment guided through the teachings of Traditional Chinese Medicine and Hippocrates. Researcher in the University of São Paulo, in the Ophthalmology department from 2012 to 2013.Author of the theory Constitutional Homeopathy of the Five Elements Based on Traditional Chinese Medicine. Author of more than 60 publications about treatment of variety of diseases rebalancing the internal energy using Hippocrates thoughts.

Abstract:

 Introduction: The earliest detection of cancer formation is the objective from all medicals systems as cancer in the early stage can be asymptomatic. A variety of techniques involving biomedical imaging are used in all phases of cancer measurements. According to traditional Chinese medicine, cancer comes from energy deficiency and Heat retention.

Purpose; the purpose of this study is to demonstrate that there are tools that we can use to screening the prevention of cancer formation without using any laboratorial or image exam.

Methods; the author used some theories in traditional Chinese medicine concerning cancer formation and applied in her daily practice. In a research she did in her clinic measuring 1000 chakras’ energy centers from 2015 to 2020, using radiesthesia procedure, to see how were the energy of the population that she was attending her clinic in Brazil.

Results; more than 90% of the patients studied were in the minimum level of energy, rated one out of eight and all of them were considered high risks for acquiring cancer due to the complete lack of energy in this chakras’ energy centers, that are the energy deficiency responsible for the cancer formation if not properly treated accordingly.

Conclusion: there are other form of prevention of cancer without using any radiological and laboratorial exams such as the use of radiesthesia procedure to measure the energy in the chakras’ energy centers, that are responsible for the formation of Yin, Yang (Kidney or second chakra), Qi (distributed by the fourth chakra and or the Blood (produced by the fifth chakra and controlled the flow of the blood inside the vessels. The detection of patient with chakras’ energy deficiency is imperative in all patients nowadays, because of the influences of the electromagnetic waves in our life, harming our energy and the treatment of this condition using traditional Chinese medicine´s tools and homeopathies medications according to the theory Constitutional Homeopathy of the Five Elements based on Traditional Chinese Medicine are very important to prevention of cancer formation in health patients nowadays.