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Arianna Calcinotto


Arianna Calcinotto

Institute of Oncology Research, Switzerland

Biography

Arianna Calcinotto is Group Leader of the Cancer Immunotherapy group at the Institute of Oncology Research in Switzerland. She received her PhD in Molecular Medicine with honors from Università Vita-Salute San Raffaele, Milan in 2015. She completed her Post Doc training before at San Raffaele Institute in Milan, then in the lab of Prof. Bergsagel at Mayo Clinic (Arizona, USA) and then in the lab of Prof. Alimonti in Switzerland. She has studied cancer cell-immune cell interactions in the tumor microenvironment during different phases of cancer development and progression in both solid tumors and hematological malignancies developing novel immunotherapies for cancer. Her major scientific contributions have been the identification of an unexpected link between the presence of specific bugs in the gut microbiota in patients affected by multiple myeloma and prostate cancer and the identification of the role played by IL23 producing myeloid cells promoting therapy-resistance in castration resistance prostate cancer patients.

Abstract

Abstract : Targeting tumour-infiltrating myeloid cells for breast cancer therapy