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Sarah Spiegel


Sarah Spiegel

Virginia Commonwealth University School of Medicine, USA

Biography

Dr. Sarah Spiegel is the Chair of the Department of Biochemistry and Molecular Biology at Virginial Commonwealth University School of Medicine and directs the Cancer Cell Signaling Program at the MCC. Her research is focused on sphingosine-1-phosphate (S1P), whose functions as a pleiotropic signaling lipid were discovered in her lab that opened a new areas of research focused on this bioactive sphingolipid metabolite. As a result of her work, it is now recognized that S1P regulates numerous biological processes and is critical for health and diseases. She has published more than 300 papers and received many awards for her work.

Abstract

Abstract : Role of sphingosine-1-phosphate in estrogen receptor signaling in breast cancer