Gia Nemsadze
The Institute of Clinical Oncology, Georgia
Title: The influence of nonstandard type operations during metastatic breast cancer
Biography
Biography: Gia Nemsadze
Abstract
Notwithstanding of recent development of diagnostics and new approaches in treatment of stage IV breast cancer disease, the treatment of metastatic Brest cancer yet remains as one of the significant problems of the medical World.
The studies and practice at our clinic has defined many different cases which included both - standard type of treatment (i.e. metastatic liver and pulmonary surgical interference); and the ones that can be considered as non-standard approach when the surgery derives from non-standard metastatic development of the breast caner. There are cases when the secondary damages were discovered in the form of ulcerated tumor of sternum; ulcerated supraclavicular area; neck lymph nodes; soft tissue damages in different areas and also combined damage of pleura with ribs.
We have carried out more than 30 non-standard operations during 2012-2016 related to the patients that has developed metastatic diseases in one of above motioned areas.
These are the patients who were not the De'novo patients and all of them have previously gone through the both: the surgical; and systemic treatment of primary breast cancer such as: chemo, target, hormone/radiation therapies.
However, the decision to go through the surgery has been taken after the resistance of the disease towards the systemic therapy was defined. In most of the cases the quality of the patients life was deteriorating because of paraneoplastic syndromes and fast growing visualized tumor development (depression, pain, ulceration, secondary infection, bleeding etc..).
Surgeries:
21 cases of supraclavicular area and neck lymph nodes. The operations included:
Neck area lymphadenectomy, or tumor conglomerate excision from supraclavicular area.
3 cases of local recurrence with tumor incision in the ribs. The operations included:
The resection of local recurrence in one block of damaged area.
2 cases of parietal pleura damage. The operations included:
Tumor atypical resection.
4 cases of total damage of sternum with adjusted problems of ulcerated and bleeding tumor.
The operations included:
combined resection of the tumor tissue together with the damaged sternum.