Lubna Mushtaque Vohra
Ziauddin University Hospital, Pakistan
Title: Metaplastic carcinoma of the breast and p16 positivity: What does it mean?
Biography
Biography: Lubna Mushtaque Vohra
Abstract
Metaplastic breast cancer are a group of breast cancer subsets which display the coexistence of breast cancer of the usual varieties along with other components such as squamous, sarcomatoid ,chondroid or other tissue types in the same specimen. The presence of p16 positivity by immunohistochemistry as a surrogate marker in HPV related oropharangeal cancer is now well accepted. Whether this is related to other such cancers of the HPV spectrum needs more research. It is with this background that five sequential cases of meta plastic breast cancer were tested for p16 positivity by IHC.