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Sribatsa Kumar Mahapatra

Sribatsa Kumar Mahapatra

VSS Institute of Medical Sciences and Research, India

Title: Autologous bone marrow therapy to operative site following modified radical mastectomy to prevent flap complications

Biography

Biography: Sribatsa Kumar Mahapatra

Abstract

Modified Radical Mastectomy is the standard surgical procedure for locally advanced Breast Cancer and other early Breast Cancer in developing countries. Breast Flap Complications like Seroma, Flap Necrosis, Marginal Flap Necrosis, Wound infection, Shoulder stiffness, hypertrophic scarp, kelloid formation & local recurrence are some of the complications seen commonly following Modified Radical Mastectomy.

Bone Marrow is harvested just before MRM from the patients sternum under anesthesia  & kept aside in heparinised solution. Flaps are raised  above & below as per standard procedure and Mastectomy completed with the tumour in toto alongwith auxiliary dissection. Haemostasis is achieved in Breast bed under the flap and axilla.

Autologous bone marrow  is infiltrated under the flap and infiltrated to axiliary walls and pectoral bed. Would closed with a dynamic drain to axila and upper flap. Post Operative observation of local pain, amount of drain collection, duration of the drain stay and shoulder stiffness symptoms are compared with a group of standard MRM without bone marrow application.

It is observed that autologus bone marrow therapy is helpful in preventing local flap problems. Postoperative pain is found to be significantly less, local seroma formation is less making early drain removal, post operative would infection is less, & shoulder stiffness is less. Regarding local hypertrophic scarp, kelloid & local recurrence we need further followup in the study.